Actraphane 50/50

From Diabetes in Pets

Actraphane 50/50
R/Neutral/NPH/Isophane Mix by Novo Nordisk
intermediate-acting	r-DNA/GE/GM
U100	isophane
Line	Novo
Also known as	Mixtard 50
Similar to	Humulin 50/50, Insuman Comb 50, Humulin M5
Action in cats	onset Xh, peak Xh duration Xh
Action in dogs	onset 0.5-3h, peak 2-10h, duration 4-24h
Use and Handling
Type	cloudy
Shelf Life	30 months
When opened	6 weeks room temp.
In pen	6 weeks room temp.
Notes	protect from light and heat Do Not Freeze Do not use if product does not re-suspend Roll Do not use intravenously

A 50% R/neutral and 50% NPH/isophane crystal mixed insulin^[1] that's intermediate-acting by Novo Nordisk.

Comparable insulins are: Humulin 50/50^[2], Mixtard 50^[3][4][5], and Insuman Comb 50^[6][7]. Eli Lilly produced an identical insulin under the name Humulin M5^[8] in the EU & UK; it was withdrawn in July 2004 from those markets^[9].

[edit] References

1. ↑ EMEA Scientific Discussion Actraphane
2. ↑ Humulin 50/50;NPH;R Human Insulin Remedyfind.com
3. ↑ EMEA Scientific Discussion-Mixtard
4. ↑ Electronic Medicines Compendium (EMC) UK-Patient Information-Mixtard 50
5. ↑ Prescribing Novo Insulins
6. ↑ Electronic Medicines Compendium (EMC) UK- Patient information Leaflet-Insuman Comb 50
7. ↑ Prescribing Insuman Insulins
8. ↑ Lilly EU/UK Product Names & Time Activity Profiles
9. ↑ Diabetes UK Google Cached Page-Withdrawal of Humulin M5-July 2004