This is a 50% insulin lispro, 50% insulin lispro protamine suspension mixed, intermediate-acting Eli Lilly analog insulin[1]. Humalog 50 [2], AKA Humalog 50/50, has a 50% fraction of crystals which consist of a combination of insulin lispro and protamine for suspension.

A study of dogs from 1993-1994 using various fractions of Humalog mixes against human NPH/isophane insulin found only minor differences in the use of Humalog Mix as opposed to NPH/isophane insulin[3].


  1. Humalog Mix 50-Insulin Lispro Protamine; Insulin Lispro
  2. FDA-Humalog
  3. US-FDA Humalog Pharmacology Review-Pages 5 & 6

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