Hypurin Vet Protamine Zinc

From Diabetes in Pets

Hypurin Vet Protamine Zinc
PZI by CP Pharma
long-acting	Bovine
U100	protamine
Line	Hypurin
Also known as	Hypurin Bovine Protamine Zinc, Hypurin Vet PZI, beef PZI
Similar to	Hypurin Bovine Protamine Zinc, Insuvet Protamine Zinc, BCP PZI, Summit PZI
Action in cats	onset 2-5h, peak 12-24h duration: maximum 36h
Action in dogs	onset 2-5h, peak 12-24h, duration: maximum 36h-rarely used[1]
Use and Handling
Type	cloudy
Shelf Life	36 months
When opened	28 days
In pen	N/A
Notes	protect from light and heat store at 2-8C Do Not Freeze Do not use if product does not re-suspend Roll Do not mix Hypurin Vet Protamine Zinc with Hypurin Vet Neutral in the same syringe Do not use intravenously Intramuscular use is not advised

Hypurin Vet Protamine Zinc is a beef-based PZI insulin^[2] made by CP Pharma^[3].

It is approved only for veterinary use and for distribution within the UK -- from abroad you can only order the human-approved equivalent, Hypurin Bovine Protamine Zinc.

Insuvet Protamine Zinc is also 100% bovine, U100 PZI.

US-compounded BCP PZI and Summit's PZI U100 strength insulin is comparable to this one.

No Combining For PZI Protamine Zinc PZI[4] insulin cannot be combined with other insulins, due to the amount of protamine in the insulin's formula[5][6].

[edit] References

1. ↑ Insulins-North American Veterinary Conference
2. ↑ Hypurin Bovine Protamine Zinc Patient Information
3. ↑ Electronic Medicines Compendium (EMC) UK-Hypurin Bovine Protamine Zinc
4. ↑ Excess Protamine in Protamine Zinc Insulin Formula
5. ↑ Comparison of Injection Techniques for Soluble and Protamine Zinc Insulins in Diabetes Mellitus PubMed-Practitioner-1975
6. ↑ British National Formulary (BNF)-Protamine Zinc Insulin (PZI) Binds to Soluble Insulin in Same Syringe