Category:Intermediate-acting

From Diabetes in Pets

Insulin with a duration of between 10 and 20 hours in humans is considered to be intermediate-acting. The listed insulins are considered intermediate-acting in humans and dogs, though not necessarily in cats. NPH normally has an erratic pattern of activity in cats, with a VERY variable peak time of from 1.5 to 6 hours and a duration of 4 to 10 hours. Page 3 of this IJPC article^[1] describes this.

Intermediate Acting Insulins
NPH/Isophane Insulins
Bovine/Beef	Hypurin Bovine Isophane
Bovine/Beef	Iletin I NPH (No longer produced.)
Porcine/Pork	Hypurin Porcine Isophane Hypurin Pork NPH
Porcine/Pork	Pork Insulatard (No longer produced.)
Porcine/Pork	Iletin II NPH (No longer produced.)
R-DNA	Humulin N, Humulin I
R-DNA	Insuman Basal
R-DNA	Novolin N, Insulatard ReliOn/Novolin NPH, Protaphane
Lente Insulins
Bovine/Beef	Hypurin Bovine Lente
Bovine/Beef	Insuvet Lente
Bovine/Beef	Iletin I Lente (No longer produced.)[2]
Porcine/Pork	Monotard Pork (No longer produced.)
Porcine/Pork	Iletin II Lente (No longer produced.)[3]
R-DNA	Monotard, Novolin L (No longer produced.)
R-DNA	Humulin L (No longer produced.)
Porcine/Pork	Caninsulin, Vetsulin
Non-analog mixed insulins
R-DNA/GE/GM 30% R/Neutral 70% NPH/isophane	Humulin 70/30, Humulin M3 Novolin 70/30 ReliOn/Novolin 70/30 Actraphane 30/70 Penmix 30[4]
R-DNA/GE/GM 30% R/Neutral 70% NPH/isophane	Mixtard 30 (No longer produced.)
R-DNA/GE/GM 50% R/Neutral 50% NPH/isophane	Humulin 50/50 Actraphane 50/50 Penmix 50[5]
R-DNA/GE/GM 50% R/Neutral 50% NPH/isophane	Humulin M5 (No longer produced.) Mixtard 50 (No longer produced.)
R-DNA/GE/GM 20% R/Neutral 80% NPH/isophane	Actraphane 20/80[6] Penmix 20
R-DNA/GE/GM 20% R/Neutral 80% NPH/isophane	Humulin M2 (No longer produced.) Mixtard 20 (No longer produced.
R-DNA/GE/GM 25% R/Neutral 75% NPH/isophane	Insuman Comb 25
R-DNA/GE/GM 15% R/Neutral 85% NPH/isophane	Insuman Comb 15
R-DNA/GE/GM 40% R/Neutral 60% NPH/isophane	Penmix 40
R-DNA/GE/GM 40% R/Neutral 60% NPH/isophane	Mixtard 40[7] (No longer produced.)
R-DNA/GE/GM 10% R/Neutral 90% NPH/isophane	Penmix 10
R-DNA/GE/GM 10% R/Neutral 90% NPH/isophane	Mixtard 10[8] (No longer produced.)
Porcine 30% R/Neutral 70% NPH/isophane	Hypurin Porcine 30/70 Mix
Porcine 30% R/Neutral 70% NPH/isophane	Pork Mixtard 30 (No longer produced.)
Analog mixed insulins
30% insulin aspart 70% insulin aspart, protamine suspension	Novolog Mix NovoMix 30[9]
25% insulin lispro 75% insulin lispro, protamine suspension	Humalog 75/25 Humalog Mix 25
50% insulin lispro 50% insulin lispro, protamine suspension	Humalog 50/50 Humalog Mix 50

[edit] References

1. ↑ International Journal of Pharmaceutical Compounding Providing Care for Diabetic Veterinary Patients-2000
2. ↑ Iletin I Lente-Beef/Pork Insulin Shown at Right
3. ↑ Carton Image-Iletin II Lente
4. ↑ Insulins & Mixtures
5. ↑ Insulins & Mixtures
6. ↑ Insulins & Mixtures
7. ↑ Insulins & Mixtures
8. ↑ Insulins & Mixtures
9. ↑ Insulins & Mixtures