Novolin N
From Diabetes in Pets
| Novolin N | |
| NPH, Isophane by Novo Nordisk | |
| intermediate-acting | r-DNA/GE/GM |
| U100 | Isophane |
| Line | Novolin |
| Also known as | Insulatard, ReliOn/Novolin NPH, Protaphane |
| Similar to | |
| Action in cats | |
| Action in dogs |
|
| Use and Handling | |
|---|---|
| Type | cloudy |
| Shelf Life | 18 months |
| When opened | 28 days room temp. |
| In pen | 28 days room temp. |
| Notes |
|
Novo Nordisk's intermediate-acting human insulin, known in some countries as Insulatard[4] or Protaphane[5].
[edit] Technical details
This type of insulin tends to have an onset of 2-4 hours, a peak action of 4-10 hours, and a total duration of 10-20 hours, in humans.
These times seem to be similar in dogs, but considerably compressed in cats, possibly because of cats' faster metabolism.
Cats seem instead to experience a 1-2 hour onset, a peak action of 4-6 hours, and a total duration of 8-12 hours maximum, according to user surveys on Felinediabetes.com
Like Humulin N[6][7], it is an isophane crystal protamine suspension insulin[8].
Other brands are: Humulin I[9][10][11] by Eli Lilly and Insuman Basal[12][13] byAventis.
[edit] Further Reading
How to use NPH insulins on cats by Kimber & Bunny and the FDMB
[edit] References
- ↑ Insulins-North American Veterinary Conference-2005
- ↑ Selecting an Insulin for Treatment of Diabetes Mellitus in Dogs & Cats-Nelson-OSU Endocrinology Symposium 2006-Page 41
- ↑ Insulins-North American Veterinary Conference-2005
- ↑ Prescribing Novo Insulins
- ↑ EMEA Scientific Discussion-Protaphane
- ↑ US FDA-Humulin N
- ↑ Humulin N NPH/Isophane Insulin Remedyfind.com
- ↑ EMEA Scientific Discussion-Insulatard
- ↑ Humulin I Prescribing Information
- ↑ Electronic Medicines Compendium (EMC) UK-Patient Information Leaflet-Humulin I
- ↑ Lilly EU/UK Product Sheet & Time Activity Profiles
- ↑ Electronic Medicines Compendium (EMC) UK-Patient Information Leaflet-Insuman Basal
- ↑ Insuman Prescribing Information
